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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
26.06
Human Site:
S25
Identified Species:
44.1
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S25
E
D
G
G
A
E
F
S
A
R
S
R
K
R
K
Chimpanzee
Pan troglodytes
XP_512559
393
44800
N19
R
S
R
K
R
K
A
N
V
A
V
D
P
D
E
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S25
E
D
G
G
A
E
F
S
A
R
S
R
K
R
K
Dog
Lupus familis
XP_541724
456
51105
P38
D
A
P
F
P
P
P
P
P
L
L
A
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S22
E
E
G
G
S
D
L
S
V
R
S
R
K
R
K
Rat
Rattus norvegicus
P39949
411
47463
S25
E
E
G
G
S
D
L
S
V
R
S
R
K
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
E24
S
Q
G
E
S
L
Q
E
L
Q
L
L
Q
T
R
Chicken
Gallus gallus
P49707
407
46720
T23
G
E
G
G
A
E
G
T
V
R
A
R
K
R
K
Frog
Xenopus laevis
Q91780
408
47153
S22
D
E
G
T
A
S
C
S
V
R
S
R
K
R
K
Zebra Danio
Brachydanio rerio
P47794
410
46612
S23
D
E
A
P
K
T
T
S
V
R
P
R
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
S129
E
L
G
F
E
P
P
S
A
K
R
Q
Q
R
L
Honey Bee
Apis mellifera
XP_394802
457
51232
S24
G
G
K
L
V
T
Q
S
S
K
R
K
R
R
A
Nematode Worm
Caenorhab. elegans
O01501
524
60567
H82
E
G
P
A
A
K
R
H
S
G
E
K
H
R
N
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
C30
D
E
N
N
L
P
M
C
T
R
K
R
K
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
0
100
0
N.A.
66.6
66.6
N.A.
6.6
60
60
40
N.A.
33.3
13.3
20
20
P-Site Similarity:
100
20
100
13.3
N.A.
86.6
86.6
N.A.
33.3
80
73.3
53.3
N.A.
53.3
40
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
36
0
8
0
22
8
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
29
15
0
0
0
15
0
0
0
0
0
8
0
8
0
% D
% Glu:
43
43
0
8
8
22
0
8
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
15
0
0
15
0
0
0
0
0
0
0
0
% F
% Gly:
15
15
58
36
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
15
0
0
0
15
8
15
58
0
50
% K
% Leu:
0
8
0
8
8
8
15
0
8
8
15
8
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
15
8
8
22
15
8
8
0
8
0
8
8
0
% P
% Gln:
0
8
0
0
0
0
15
0
0
8
0
8
22
0
0
% Q
% Arg:
8
0
8
0
8
0
8
0
0
58
15
58
8
72
15
% R
% Ser:
8
8
0
0
22
8
0
58
15
0
36
0
0
0
8
% S
% Thr:
0
0
0
8
0
15
8
8
8
0
0
0
0
15
0
% T
% Val:
0
0
0
0
8
0
0
0
43
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _